The first colony established in the New World under Spain was in 1492 called Santo Domingo or officially called Captaincy General of Santo Domingo. They held this colony until July 22, 1795, when the French Republic and Spanish crown signed the Treaty of Basle and the colony was ceded to France. | The first colony established in the New World under Spain was in 1492 called Santo Domingo or officially called Captaincy General of Santo Domingo. They held this colony until July 22, 1795, when the French Republic and Spanish crown signed the Treaty of Basle and the colony was ceded to France. |